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Info
Applications | ELISA IF WB |
Antigen/Gene or Protein Targets | FOSB |
Reactivity | Human and Mouse |
Relevance | FosB interacts with Jun proteins enhancing their DNA binding activity. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Host | Rabbit |
Immunogen | 3 synthetic peptides (human) conjugated to KLH |
Formulation | 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal. |
Method of Purification | Immunogen affinity purification |
Molecular Weight (kDa) | 35.96 & 31.5 |
Research Area | Cancer, Epigenetics & Nuclear Signalling |
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