Anti-MTBP [2C1E11]
Invented at University of Liverpool
Catalogue Number | 152835 |
Applications | WB |
Antigen/Gene or Protein Targets | MTBP |
Synonyms |
MDM2 Binding Protein, MDM2 (Mouse Double Minute 2)-Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein (Mouse) Binding Protein, Mdm2, Transformed 3T3 Cell Double Minute 2, P53 Binding Protein Binding Protein, MDM2BP, HMTBP |
Reactivity | Human and Mouse |
Relevance | MTBP is an MDM2 binding protein that alters p53/MDM2 homeostasis and may contribute to metastatic suppression. Recent studies have demonstrated that loss of MTBP expression in samples that are p53 positive and have low MDM2 is significantly associated with reduced patient survival in Squamous cell carcinoma of the head and neck (SCCHN). |
Host | Mouse |
Immunogen | Recombinant full-length human MTBP |
Notes | Clone also known as 15 or T15. |
Research Area | Cancer, Cell Cycle, Epigenetics & Nuclear Signalling |
There are 0 reference entries for this reagent.