SVCT-MI2 Cell Line
Invented by Prof Joyce Taylor-Papadimitriou at Cancer Research UK London Research Institute: Lincoln's Inn Fields
SVCT Cell Line
Invented by Dr Sidney Chang at Retired Consultant
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Info
| Catalogue Number | 152701 |
| Host | Human |
| Tissue | Breast |
| Disease Keywords | Breast cancer |
| Model | Immortalised Line |
| Relevance | SVCT has been established from human breast epithelial cells being transfected with SV40. The cell line shows an abnormal karyotype and was not tumourigenic in athymic male nude mice. SVCT have been found positive for the expression of keratin 7, 8 and 18 but negative for keratin 19. Epithelial cells, dome formation when confluent. |
| Conditional | No |
| Research Area | Cancer, Drug Discovery & Development |
| Growth/Phenotype Keywords | Adherent |
| Recommended Growing Conditions | DMEM + 2mM Glutamine + 5µg/ml Hydrocortisone + 10µg/ml Insulin + 10% Foetal Bovine Serum (FBS). |
| Cellosaurus ID | CVCL_2718 |
References: 2 entries
Chang et al. 1986. Biochim Biophys Acta. 823(3):161-94. PMID: 2423124.
In vitro transformation of human epithelial cells.
Europe PMC ID: 2423124
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References: 2 entries
Chang et al. 1986. Biochim Biophys Acta. 823(3):161-94. PMID: 2423124.
In vitro transformation of human epithelial cells.
Europe PMC ID: 2423124
Add a reference
References: 2 entries
Chang et al. 1986. Biochim Biophys Acta. 823(3):161-94. PMID: 2423124.
In vitro transformation of human epithelial cells.
Add a reference
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