Anti-HLA-DR [TAL 16.1]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 152692 |
| Applications | ELISA FACS IHC WB |
| Antigen/Gene or Protein Targets | Human leukocyte antigens DR16, 103, 11, 12, 13, 8, 7, 4 (Dw10 only), DR51 |
| Reactivity | Human |
| Relevance | Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 16.1 is useful for distinguishing DR1 homozygotes from DR1, DR103 heterozygotes. |
| Host | Mouse |
| Immunogen | Mouse L cell transfected with a Human HLA Class II (HLADRB5*0101) gene |
| Subclass | IgG2a |
| Myeloma Used | NS0 |
| Research Area | Immunology |
References: 4 entries
Sadler et al. 1993. Tissue Antigens. 41(1):42-6. PMID: 7681224.
The monoclonal antibody TAL16.1 recognizes the aspartic acid residue at position 70 in DRB gene products.
Europe PMC ID: 7681224
Altmann et al. 1990. Immunogenetics. 32(1):51-5. PMID: 1695613.
Fine mapping of HLA class II monoclonal antibody specificities using transfected L cells.
Europe PMC ID: 1695613
Add a reference
References: 4 entries
Sadler et al. 1993. Tissue Antigens. 41(1):42-6. PMID: 7681224.
The monoclonal antibody TAL16.1 recognizes the aspartic acid residue at position 70 in DRB gene products.
Altmann et al. 1990. Immunogenetics. 32(1):51-5. PMID: 1695613.
Fine mapping of HLA class II monoclonal antibody specificities using transfected L cells.
Add a reference
