Cat. #152692
Anti-HLA-DR [TAL 16.1]
Cat. #: 152692
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-5 days
Target: Human leukocyte antigens DR16, 103, 11, 12, 13, 8, 7, 4 (Dw10 only), DR51
Class: Monoclonal
Application: ELISA ; FACS ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julia Bodmer
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-HLA-DR [TAL 16.1]
- Clone: TAL 16.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 29 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; WB
- Description: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 16.1 is useful for distinguishing DR1 homozygotes from DR1, DR103 heterozygotes.
- Immunogen: Mouse L cell transfected with a Human HLA Class II (HLADRB5*0101) gene
- Isotype: IgG2a
- Myeloma used: NS0
Target Details
- Target: Human leukocyte antigens DR16, 103, 11, 12, 13, 8, 7, 4 (Dw10 only), DR51
- Molecular weight: 29 kDa
- Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). TAL 16.1 is useful for distinguishing DR1 homozygotes from DR1, DR103 heterozygotes.
Applications
- Application: ELISA ; FACS ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Sadler et al. 1993. Tissue Antigens. 41(1):42-6. PMID: 7681224.
- The monoclonal antibody TAL16.1 recognizes the aspartic acid residue at position 70 in DRB gene products.
- Altmann et al. 1990. Immunogenetics. 32(1):51-5. PMID: 1695613.
- Fine mapping of HLA class II monoclonal antibody specificities using transfected L cells.
