Anti-Leg1 [1G1]

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References (2)

Inventor Info

Info

Catalogue Number	152643
Applications	IF
Antigen/Gene or Protein Targets	Liver-enriched gene 1 (previously called D12)
Reactivity	Zebrafish
Relevance	Leg1 is a novel protein of 361 amino acids. Preliminary data suggested that Leg1 (previously named as D12) is involved in early liver development. However, no detailed characterization of Leg1 has been reported thus far. There are two copies of leg1 in zebrafish, namely leg1a and leg1b. Both leg1a and leg1b are expressed in the larvae and adult liver with leg1a being the predominant form. Knockdown of Leg1a or Leg1b by their respective morpholinos specifically targeting their 59-UTR each resulted in a small liver phenotype, demonstrating that both Leg1a and Leg1b are important for early liver development.
Host	Mouse
Immunogen	GST-Leg 1 fusion protein
Subclass	IgG1
Myeloma Used	Sp2/0-Ag14
Research Area	Aquaculture

There are 2 reference entries for this reagent.

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Chang et al. 2011. PLoS One. 6(8):e22910. PMID: 21857963.

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liver-enriched gene 1a and 1b encode novel secretory proteins essential for normal liver development in zebrafish.

Europe PMC ID: 21857963

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Chang et al. 2011. PLoS One. 6(8):e22910. PMID: 21857963.

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liver-enriched gene 1a and 1b encode novel secretory proteins essential for normal liver development in zebrafish.

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	A*STAR Accelerate Technologies Pte Ltd
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