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Anti-Leg1 [1G1]

Info

Catalogue Number 152643
Applications IF
Antigen/Gene or Protein Targets Liver-enriched gene 1 (previously called D12)
Reactivity Zebrafish
Relevance Leg1 is a novel protein of 361 amino acids. Preliminary data suggested that Leg1 (previously named as D12) is involved in early liver development. However, no detailed characterization of Leg1 has been reported thus far.

There are two copies of leg1 in zebrafish, namely leg1a and leg1b. Both leg1a and leg1b are expressed in the larvae and adult liver with leg1a being the predominant form. Knockdown of Leg1a or Leg1b by their respective morpholinos specifically targeting their 59-UTR each resulted in a small liver phenotype, demonstrating that both Leg1a and Leg1b are important for early liver development.
Host Mouse
Immunogen GST-Leg 1 fusion protein
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Research Area Aquaculture

References: 1 entry

Chang et al. 2011. PLoS One. 6(8):e22910. PMID: 21857963.


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References: 1 entry

Chang et al. 2011. PLoS One. 6(8):e22910. PMID: 21857963.


Add a reference

References: 1 entry

Chang et al. 2011. PLoS One. 6(8):e22910. PMID: 21857963.


Add a reference


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