Cat. #152643
Anti-Leg1 [1G1]
Cat. #: 152643
Unit size: 100 ug
Availability: 3-5 days
Target: Liver-enriched gene 1 (previously called D12)
Class: Monoclonal
Application: IF
Reactivity: Zebrafish
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Leg1 [1G1]
- Clone: 1G1
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Zebrafish
- Host: Mouse
- Application: IF
- Description: Leg1 is a novel protein of 361 amino acids. Preliminary data suggested that Leg1 (previously named as D12) is involved in early liver development. However, no detailed characterization of Leg1 has been reported thus far. There are two copies of leg1 in zebrafish, namely leg1a and leg1b. Both leg1a and leg1b are expressed in the larvae and adult liver with leg1a being the predominant form. Knockdown of Leg1a or Leg1b by their respective morpholinos specifically targeting their 59-UTR each resulted in a small liver phenotype, demonstrating that both Leg1a and Leg1b are important for early liver development.
- Immunogen: GST-Leg 1 fusion protein
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Liver-enriched gene 1 (previously called D12)
- Target background: Leg1 is a novel protein of 361 amino acids. Preliminary data suggested that Leg1 (previously named as D12) is involved in early liver development. However, no detailed characterization of Leg1 has been reported thus far. There are two copies of leg1 in zebrafish, namely leg1a and leg1b. Both leg1a and leg1b are expressed in the larvae and adult liver with leg1a being the predominant form. Knockdown of Leg1a or Leg1b by their respective morpholinos specifically targeting their 59-UTR each resulted in a small liver phenotype, demonstrating that both Leg1a and Leg1b are important for early liver development.
Applications
- Application: IF
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Chang et al. 2011. PLoS One. 6(8):e22910. PMID: 21857963
