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Anti-EGFR, Recombinant [EGFR1]

Invented by Dr Peter Goodfellow at Abingworth Life Sciences

Info

Catalogue Number 152583
Applications FACS IHC IF IP WB
Antigen/Gene or Protein Targets Epidermal Growth Factor Receptor (EGFR, Her1)
Reactivity Human
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). Dysregulation of EGFR signaling as a consequence of overexpression, amplification and mutation of the EGFR gene occurs frequently in several types of cancers and many become dependent on EGFR signaling to maintain their malignant phenotypes.
Host Mouse
Immunogen Human epidermoid carcinoma line A431
Subclass IgG2b
Formulation PBS only
Concentration 1mg/ml
Molecular Weight (kDa) 175
Research Area Cancer, Cell Signaling & Signal Transduction
Notes Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

References: 1 entry

Original hybridoma first published in Waterfield et al. 1982. J Cell Biochem. 20(2):149-61. PMID: 6188757.


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References: 1 entry

Original hybridoma first published in Waterfield et al. 1982. J Cell Biochem. 20(2):149-61. PMID: 6188757.


Add a reference

References: 1 entry

Original hybridoma first published in Waterfield et al. 1982. J Cell Biochem. 20(2):149-61. PMID: 6188757.


Add a reference


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