Anti-ADAM9, Polyclonal [9MO]
Invented by Prof Carl Blobel from Hospital For Special Surgery At Weill Cornell Medicine
Invented at
- Datasheet
- References (8)
- Inventor Info
Info
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| Catalogue Number | 152538 |
| Applications | WB |
| Antigen/Gene or Protein Targets | ADAM9 |
| Reactivity | Mouse |
| Relevance | ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. |
| Host | Rabbit |
| Immunogen | GST-cyto corresponding to the cytoplasmic domain of murine ADAM9 |
| Formulation | Whole serum |
| Molecular Weight (kDa) | ~84 (mature form), 115 (pro-form) |
| Notes | Suggested dilution for western blot: 1:500 |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
References: 8 entries
Guaiquil et al. 2009. Mol Cell Biol. 29(10):2694-703. PMID: 19273593.
Peduto et al. 2005. Cancer Res. 65(20):9312-9. PMID: 16230393.
Roghani et al. 1999. J Biol Chem. 274(6):3531-40. PMID: 9920899.
ADAM9 is involved in pathological retinal neovascularization.
Europe PMC ID: 19273593
Critical function for ADAM9 in mouse prostate cancer.
Europe PMC ID: 16230393
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.
Europe PMC ID: 9920899
Weskamp et al. 1996. J Cell Biol. 132(4):717-26. PMID: 8647900.
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
Europe PMC ID: 8647900
Add a reference
References: 8 entries
Guaiquil et al. 2009. Mol Cell Biol. 29(10):2694-703. PMID: 19273593.
Peduto et al. 2005. Cancer Res. 65(20):9312-9. PMID: 16230393.
Roghani et al. 1999. J Biol Chem. 274(6):3531-40. PMID: 9920899.
ADAM9 is involved in pathological retinal neovascularization.
Critical function for ADAM9 in mouse prostate cancer.
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.
Weskamp et al. 1996. J Cell Biol. 132(4):717-26. PMID: 8647900.
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
Add a reference
