Cancer Research Technology
Log in Register
Menu

Info

Catalogue Number 152538
Applications WB
Antigen/Gene or Protein Targets ADAM9
Reactivity Mouse
Relevance ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
Host Rabbit
Immunogen GST-cyto corresponding to the cytoplasmic domain of murine ADAM9
Formulation Whole serum
Molecular Weight (kDa) ~84 (mature form), 115 (pro-form)
Notes Suggested dilution for western blot: 1:500
Research Area Cancer, Cell Signaling & Signal Transduction

References

There are 8 reference entries for this reagent.

View All References

References: 8 entries

Guaiquil et al. 2009. Mol Cell Biol. 29(10):2694-703. PMID: 19273593.

Peduto et al. 2005. Cancer Res. 65(20):9312-9. PMID: 16230393.

Roghani et al. 1999. J Biol Chem. 274(6):3531-40. PMID: 9920899.

ADAM9 is involved in pathological retinal neovascularization.

Europe PMC ID: 19273593

Critical function for ADAM9 in mouse prostate cancer.

Europe PMC ID: 16230393

Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.

Europe PMC ID: 9920899

Weskamp et al. 1996. J Cell Biol. 132(4):717-26. PMID: 8647900.

MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.

Europe PMC ID: 8647900


Add a reference

References: 8 entries

Guaiquil et al. 2009. Mol Cell Biol. 29(10):2694-703. PMID: 19273593.

Peduto et al. 2005. Cancer Res. 65(20):9312-9. PMID: 16230393.

Roghani et al. 1999. J Biol Chem. 274(6):3531-40. PMID: 9920899.

ADAM9 is involved in pathological retinal neovascularization.

Critical function for ADAM9 in mouse prostate cancer.

Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.

Weskamp et al. 1996. J Cell Biol. 132(4):717-26. PMID: 8647900.

MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.


Add a reference