Cat. #152538
Anti-ADAM9 [9MO]
Cat. #: 152538
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: ADAM9
Class: Polyclonal
Application: WB
Reactivity: Mouse
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Carl Blobel
Institute: Hospital for Special Surgery
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-ADAM9 [9MO]
- Clone: 9MO
- Tool sub type: Primary antibody
- Class: Polyclonal
- Conjugation: Unconjugated
- Molecular weight: ~84 kDa (mature form), 115 kDa (pro-form)
- Reactivity: Mouse
- Host: Rabbit
- Application: WB
- Description: ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
- Immunogen: GST-cyto corresponding to the cytoplasmic domain of murine ADAM9
Target Details
- Target: ADAM9
- Molecular weight: ~84 kDa (mature form), 115 kDa (pro-form)
- Target background: ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: Whole serum
- Storage conditions: -20° C
- Shipping conditions: Shipping at 4° C
References
- Guaiquil et al. 2009. Mol Cell Biol. 29(10):2694-703. PMID: 19273593.
- Peduto et al. 2005. Cancer Res. 65(20):9312-9. PMID: 16230393.
- Roghani et al. 1999. J Biol Chem. 274(6):3531-40. PMID: 9920899.
- ADAM9 is involved in pathological retinal neovascularization.
- Critical function for ADAM9 in mouse prostate cancer.
- Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity.
- Weskamp et al. 1996. J Cell Biol. 132(4):717-26. PMID: 8647900.
- MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
