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|Antigen/Gene or Protein Targets||MSP-2 (type A)|
|Relevance||In considering methods for immunological control of Plasmodium falciparum malaria it is essential to know more about antigenic diversity within and between natural populations of the parasite from major endemic areas. A successful malaria vaccine would stimulate an individual's immune system to respond to the malaria parasite and prevent serious clinical disease. Many different groups are currently developing potential vaccines. Several Plasmodium falciparum genes show extensive genetic polymorphism. This phenomenon is exploited for genetic finger printing and for assessing parasite population dynamics. For instance, high polymorphism has been shown in msp1, msp2 and glurp genes in different geographical locations in malaria endemic areas|
|Immunogen||Schizonts (T9 isolate as immunogen)|
Recognises the Block 3 region of MSP-2 of the 3D7/IC1 type (type A).
UK Biosafety level: 1
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