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Anti-ASPP2 [DX54.10]

Info

Applications IP WB
Antigen/Gene or Protein Targets ASPP2
Reactivity Human, Mouse and Rabbit
Relevance The apoptosis stimulating proteins of p53 (ASPP) family consists of three members, ASPP1, ASPP2 and iASPP. They bind to proteins that are key players in controlling apoptosis (p53, Bcl-2 and RelA/p65) and cell growth (APCL, PP1). So far, the best-known function of the ASPP family members is their ability to regulate the apoptotic function of p53 and its family members, p63 and p73. Biochemical and genetic evidence has shown that ASPP1 and ASPP2 activate, whereas iASPP inhibits, the apoptotic but not the cell-cycle arrest function of p53.
Host Mouse
Research Area Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, Stem Cell Biology

References: 1 entry

Samuels-Lev et al. 2001. Mol Cell. 8(4):781-94. PMID: 11684014.


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References: 1 entry

Samuels-Lev et al. 2001. Mol Cell. 8(4):781-94. PMID: 11684014.


Add a reference

References: 1 entry

Samuels-Lev et al. 2001. Mol Cell. 8(4):781-94. PMID: 11684014.


Add a reference


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