Anti-Cytochrome P450 8B1 [M15-P3B7]

Datasheet

References (2)

Inventor Info

Info

Catalogue Number	152155
Applications	ELISA IHC WB
Antigen/Gene or Protein Targets	Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)
Reactivity	Human and Rat
Relevance	Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
Host	Mouse
Immunogen	Peptide sequence– QPSHDVRFR (amino acids 486 – 494)
Positive Control	ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver
Subclass	IgG1 kappa
Myeloma Used	P3X63Ag8.653
Recommended Growing Conditions	Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine).
Strain	Balb/c
Notes	This antibody was applied in a poster presented at the 2015 NCRI conference: http://abstracts.ncri.org.uk/?s=oxysterol&year_published=2015
Research Area	Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

There are 2 reference entries for this reagent.

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Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

Europe PMC ID: 27341022

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Swan et al. 2016. Oncotarget. :. PMID: 27341022.

IHC WB

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Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

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Swan et al. 2016. Oncotarget. :. PMID: 27341022.

IHC WB

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	Ayham Alnabulsi
	from Vertebrate Antibodies Limited Linked to 154 other reagents on Ximbio.

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	Vertebrate Antibodies Limited
	199 reagents listed on Ximbio

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