#152155

Anti-Cytochrome P450 8B1 [M15-P3B7]

Cat. #152155

Anti-Cytochrome P450 8B1 [M15-P3B7]

Cat. #: 152155

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human ; Rat

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Cytochrome P450 8B1 [M15-P3B7]
  • Clone: M15-P3B7
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human ; Rat
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
  • Immunogen: Peptide sequence QPSHDVRFR (amino acids 486 494)
  • Isotype: IgG1 kappa
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver

Target Details

  • Target: Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1)
  • Tissue cell line specificity: ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC- Human liver
  • Target background: Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
  • Swan et al. 2016. Oncotarget. :. PMID: 27341022.