Anti-Cytochrome P450 39A1 [M30P6D6]

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References (2)

Inventor Info

Info

Catalogue Number	152122
Applications	ELISA IHC WB
Antigen/Gene or Protein Targets	CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.
Reactivity	Human
Relevance	CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-α-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
Host	Mouse
Immunogen	Ovalbumin-conjugated synthetic peptide CRIEYKQRI (C-terminal sequence).
Positive Control	IHC: formalin-fixed, paraffin-embedded human liver sections. WB: pooled human liver microsomes.
Subclass	IgG3 kappa
Subclass Notes	Presence of IgG confirmed by H and L chains on SDS-PAGE
Myeloma Used	P3X63Ag8.653
Recommended Growing Conditions	Dulbecco’s media containing L-Glutamine and 20% Fetal Bovine serum (DH20).
Notes	This antibody was applied in a poster presented at the 2015 NCRI conference: http://abstracts.ncri.org.uk/?s=oxysterol&year_published=2015
Research Area	Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

There are 2 reference entries for this reagent.

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Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

Europe PMC ID: 27341022

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Swan et al. 2016. Oncotarget. :. PMID: 27341022.

IHC WB

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Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

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Swan et al. 2016. Oncotarget. :. PMID: 27341022.

IHC WB

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	Ayham Alnabulsi
	from Vertebrate Antibodies Limited Linked to 154 other reagents on Ximbio.

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	Vertebrate Antibodies Limited
	199 reagents listed on Ximbio

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