#152122

Anti-Cytochrome P450 39A1 [M30P6D6]

Cat. #152122

Anti-Cytochrome P450 39A1 [M30P6D6]

Cat. #: 152122

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Cytochrome P450 39A1 [M30P6D6]
  • Clone: M30P6D6
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-Î?-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
  • Immunogen: Ovalbumin-conjugated synthetic peptide CRIEYKQRI (C-terminal sequence).
  • Isotype: IgG3 kappa
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: IHC: formalin-fixed, paraffin-embedded human liver sections. WB: pooled human liver microsomes.

Target Details

  • Target: CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.
  • Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded human liver sections. WB: pooled human liver microsomes.
  • Target background: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-a-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
  • Swan et al. 2016. Oncotarget. :. PMID: 27341022.