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Anti-Cytochrome P450 39A1 [M30P6D6]

Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited

Info

Catalogue Number 152122
Applications ELISA IHC WB
Antigen/Gene or Protein Targets CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.
Reactivity Human
Relevance CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-α-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide CRIEYKQRI (C-terminal sequence).
Positive Control IHC: formalin-fixed, paraffin-embedded human liver sections. WB: pooled human liver microsomes.
Subclass IgG3 kappa
Subclass Notes Presence of IgG confirmed by H and L chains on SDS-PAGE
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions Dulbecco’s media containing L-Glutamine and 20% Fetal Bovine serum (DH20).
Notes This antibody was applied in a poster presented at the 2015 NCRI conference: http://abstracts.ncri.org.uk/?s=oxysterol&year_published=2015
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

References

There are 2 reference entries for this reagent.

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References: 2 entries

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

Europe PMC ID: 27341022

Swan et al. 2016. Oncotarget. :. PMID: 27341022.

IHC WB


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References: 2 entries

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

Swan et al. 2016. Oncotarget. :. PMID: 27341022.

IHC WB


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