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Anti-BORIS [4A7]

Invented by Prof Elena Klenova at University of Essex

Info

Catalogue Number 151848
Applications ChIP ELISA IF IP WB
Antigen/Gene or Protein Targets BORIS
Synonyms Brother of the regulator of imprinted sites, Cancer/testis antigen 27, CCCTC binding factor (zinc finger protein) like, CCCTC-binding factor, CT27, CTCF paralog, CTCF T, CTCF-like protein, Ctcfl, CTCFL_HUMAN, dJ579F20.2, HMG 1L1, HMGB1L1, MGC163358, MGC169105, MGC169106
Reactivity Human
Relevance Reagent for research, diagnostic tool. BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly responsible for the transcriptional activation of TSP50 (testes-specific protease 50).
Host Mouse
Immunogen The N-terminal domain (aa 2-257) of human BORIS (CTCFL) protein, expressed in E.coli
Subclass IgM kappa
Positive Control Testis
Molecular Weight (kDa) 83
Recommended Growing Conditions HM20-10% HCF (Further details in remarks)
Notes Protein L beads should be used for ChIP and IP because this antibody is IgM kappa

Staining Pattern: May be nuclear, cytoplasmic or both (depending on cell type)
Research Area Cancer, Epigenetics & Nuclear Signalling

References: 1 entry

Cheema et al. 2014. Prostate. 74(2):164-76. PMID: 24123052.


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References: 1 entry

Cheema et al. 2014. Prostate. 74(2):164-76. PMID: 24123052.


Add a reference

References: 1 entry

Cheema et al. 2014. Prostate. 74(2):164-76. PMID: 24123052.


Add a reference


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