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Anti-BLK [BLK154/D4]

Invented by Dr Jacqueline Cordell at University of Oxford

Info

Catalogue Number 151789
Applications WB
Antigen/Gene or Protein Targets BLK
Reactivity Human
Relevance B lymphoid tyrosine kinase is a member of the src family of proto-oncogenes that are involved in cell proliferation and differentiation1. It is expressed in B cells during all stages of development and has a role in B-cell receptor signaling and B-cell development2,3. BLK also stimulates insulin synthesis and secretion in response to glucose by up regulating pancreatic beta-cell transcription factors.
Host Mouse
Immunogen Recombinant protein corresponding to amino acids 53- 224 of human BLK
Subclass IgG1
Positive Control Human B cell line
Myeloma Used NS0
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Research Area Apoptosis and Programmed Cell Death

References: 4 entries

Borowiec et al. 2009. Proc Natl Acad Sci U S A. 106(34):14460-5. PMID: 19667185.

Wasserman et al. 1995. J Immunol. 155(2):644-51. PMID: 7608542.

Islam et al. 1995. J Immunol. 154(3):1265-72. PMID: 7822795.

Yao et al. 1993. Proc Natl Acad Sci U S A. 90(17):7946-50. PMID: 7690139.


Add a reference

References: 4 entries

Borowiec et al. 2009. Proc Natl Acad Sci U S A. 106(34):14460-5. PMID: 19667185.

Wasserman et al. 1995. J Immunol. 155(2):644-51. PMID: 7608542.

Islam et al. 1995. J Immunol. 154(3):1265-72. PMID: 7822795.

Yao et al. 1993. Proc Natl Acad Sci U S A. 90(17):7946-50. PMID: 7690139.


Add a reference

References: 4 entries

Borowiec et al. 2009. Proc Natl Acad Sci U S A. 106(34):14460-5. PMID: 19667185.

Wasserman et al. 1995. J Immunol. 155(2):644-51. PMID: 7608542.

Islam et al. 1995. J Immunol. 154(3):1265-72. PMID: 7822795.

Yao et al. 1993. Proc Natl Acad Sci U S A. 90(17):7946-50. PMID: 7690139.


Add a reference


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