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Anti-ASPP1, Polyclonal [ASPP1]

Info

Catalogue Number 151751
Applications IF IP WB
Antigen/Gene or Protein Targets ASPP1
Reactivity Human
Relevance Stimulating protein of p53 (ASPP) contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. There are three known types of ASPP: ASPP1, ASPP2 and iASPP1. iASPP1 inhibits the proaptotic functions of ASPP1 and p53.
Host Sheep
Immunogen Amino acids from human ASPP1 357-532
Research Area Cancer, Stem Cell Biology

References: 2 entries

Thornton et al. 2006. Oncogene. 25(22):3104-12. PMID: 16474851.

The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.

Europe PMC ID: 16474851


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References: 2 entries

Thornton et al. 2006. Oncogene. 25(22):3104-12. PMID: 16474851.

The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.

Europe PMC ID: 16474851


Add a reference

References: 2 entries

Thornton et al. 2006. Oncogene. 25(22):3104-12. PMID: 16474851.

The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.


Add a reference


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