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Anti-ENTPD1 [AC2]


Catalogue Number 151580
Applications FACS IF IP WB
Antigen/Gene or Protein Targets Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1, CD39)
Reactivity Human
Relevance ENTPD1 is a transmembrane glycoprotein of apparent molecular weight of 70-100 kD that has an Ectonucleoside triphosphate diphosphohydrolase-1 (NTPDase-1, ecto-apyrase) activity hydrolyzing the alpha- and beta- phosphate residues of extracellular ATP or ADP. In haematopoietic tissues, it is primarily expressed on activated B, T and NK cells. It is also expressed on some endothelial cells and cardiac neurons, and helps regulate platelet activation, vascular inflammation, and cardiac norepinephrine release.
Host Mouse
Immunogen EBV-transformed human B lymphoblastoid cell line
Subclass IgG1
Positive Control EBV-transformed human B lymphoblastoid cell line
Molecular Weight (kDa) 70-100
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes Recommended Concentrations:

FACS: 1µg/5x105 cells

Immunofluorescence on acetone-fixed frozen sections or cell smears: 1-2µg/ml

Western blot (ECL): 0.2µg/ml
Research Area Cardiovascular, Cell Type or Organelle Marker, Immunology, Neurobiology

References: 1 entry

Rowe et al. 1982. Int J Cancer. 29(4):373-81. PMID: 6282762.

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