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Anti-APC5 [APC5#4]

Invented by Dr Andy Turnell from University Of Birmingham
Invented at University Of Birmingham

Info

Catalogue Number 151567
Applications IF IP WB
Antigen/Gene or Protein Targets Anaphase-promoting complex subunit 5 (APC5)
Synonyms Anaphase-promoting complex subunit 5; RMC1; YOR249C
Reactivity Human
Relevance APC5 is a component of the anaphase-promoting complex/cyclosome (APC) that regulates cell cycle progression through mitosis and G1. APC5 is located in the nucleus during interphase and at the centrosome during metaphase/anaphase. The APC is inactivated by protein kinase A and is activated by CDC20 and Cdh1.
Host Mouse
Immunogen GST-human APC5
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DME/Hepes + 8% FCS + 2mM Glutamine
Strain C57BL/6
Research Area Cell Cycle, Protein Degradation

References

There are 2 reference entries for this reagent.

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References: 2 entries

Turnell et al. 2005. Nature. 438(7068):690-5. PMID: 16319895.

The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression.

Europe PMC ID: 16319895


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References: 2 entries

Turnell et al. 2005. Nature. 438(7068):690-5. PMID: 16319895.

The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression.


Add a reference