#151567

Anti-APC5 [APC5#4]

Cat. #151567

Anti-APC5 [APC5#4]

Cat. #: 151567

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Anaphase-promoting complex subunit 5 (APC5)

Class: Monoclonal

Application: IF ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Andy Turnell

Institute: University of Birmingham

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-APC5 [APC5#4]
  • Alternate name: Anaphase-promoting complex subunit 5; RMC1; YOR249C
  • Clone: APC5#4
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Strain: C57BL/6
  • Reactivity: Human
  • Host: Mouse
  • Application: IF ; IP ; WB
  • Description: APC5 is a component of the anaphase-promoting complex/cyclosome (APC) that regulates cell cycle progression through mitosis and G1. APC5 is located in the nucleus during interphase and at the centrosome during metaphase/anaphase. The APC is inactivated by protein kinase A and is activated by CDC20 and Cdh1.
  • Immunogen: GST-human APC5
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Anaphase-promoting complex subunit 5 (APC5)
  • Tissue cell line specificity: Human
  • Target background: APC5 is a component of the anaphase-promoting complex/cyclosome (APC) that regulates cell cycle progression through mitosis and G1. APC5 is located in the nucleus during interphase and at the centrosome during metaphase/anaphase. The APC is inactivated by protein kinase A and is activated by CDC20 and Cdh1.

Applications

  • Application: IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Turnell et al. 2005. Nature. 438(7068):690-5. PMID: 16319895.
  • The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression.