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Anti-Zebrafish DeltaC [zdc2]

Invented by Dr Gavin Wright at Wellcome Trust Sanger Institute

Info

Catalogue Number 151510
Applications ELISA FACS IHC IF WB
Antigen/Gene or Protein Targets Zebrafish DeltaC
Reactivity Zebrafish
Relevance Delta proteins activate Notch through a binding reaction that depends on their extracellular domains. During somitogenesis, Notch signalling via DeltaC keeps the oscillations of neighbouring cells in synchrony. DeltaC is also expressed in subsets of cells in the nervous system and elsewhere.
Host Mouse
Immunogen Extracellular region of zebrafish DeltaC protein
Subclass IgG2a
Positive Control HEK293 cells transfected with DeltaD and Zebrafish embryo cryosections (formulin fixed)
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Research Area Aquaculture, Cell Cycle, Developmental Biology, Neurobiology

References: 4 entries

Wright et al. 2011. Development. 138(14):2947-56. PMID: 21653612.

DeltaC and DeltaD interact as Notch ligands in the zebrafish segmentation clock.

Europe PMC ID: 21653612

Giudicelli et al. 2007. PLoS Biol. 5(6):e150. PMID: 17535112.

Setting the tempo in development: an investigation of the zebrafish somite clock mechanism.

Europe PMC ID: 17535112


Add a reference

References: 4 entries

Wright et al. 2011. Development. 138(14):2947-56. PMID: 21653612.

DeltaC and DeltaD interact as Notch ligands in the zebrafish segmentation clock.

Europe PMC ID: 21653612

Giudicelli et al. 2007. PLoS Biol. 5(6):e150. PMID: 17535112.

Setting the tempo in development: an investigation of the zebrafish somite clock mechanism.

Europe PMC ID: 17535112


Add a reference

References: 4 entries

Wright et al. 2011. Development. 138(14):2947-56. PMID: 21653612.

DeltaC and DeltaD interact as Notch ligands in the zebrafish segmentation clock.

Giudicelli et al. 2007. PLoS Biol. 5(6):e150. PMID: 17535112.

Setting the tempo in development: an investigation of the zebrafish somite clock mechanism.


Add a reference


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