Cancer Research Technology
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Catalogue Number 151485
Applications FACS IHC IP
Antigen/Gene or Protein Targets Integrin alpha 2 subunit (CD49b)
Reactivity N/A
Relevance Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
Host Mouse
Subclass IgG2a
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Research Area Adhesion, Cancer, Cell Signaling & Signal Transduction, Metabolism

References

There are 4 reference entries for this reagent.

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References: 4 entries

Sugiyama et al. 1993. Carcinogenesis. 14(10):2171-6. PMID: 7693359.

Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas.

Europe PMC ID: 7693359

Tenchini et al. 1993. Cell Adhes Commun. 1(1):55-66. PMID: 7521749.

Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes.

Europe PMC ID: 7521749


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References: 4 entries

Sugiyama et al. 1993. Carcinogenesis. 14(10):2171-6. PMID: 7693359.

Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas.

Tenchini et al. 1993. Cell Adhes Commun. 1(1):55-66. PMID: 7521749.

Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes.


Add a reference