#151485

Anti-Integrin a2 [HAS-6]

Cat. #151485

Anti-Integrin a2 [HAS-6]

Cat. #: 151485

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Integrin alpha 2 subunit (CD49b)

Class: Monoclonal

Application: FACS ; IHC ; IP

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Fiona Watt

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Integrin a2 [HAS-6]
  • Clone: HAS-6
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Host: Mouse
  • Application: FACS ; IHC ; IP
  • Description: Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Integrin alpha 2 subunit (CD49b)
  • Target background: Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.

Applications

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Sugiyama et al. 1993. Carcinogenesis. 14(10):2171-6. PMID: 7693359.
  • Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas.
  • Tenchini et al. 1993. Cell Adhes Commun. 1(1):55-66. PMID: 7521749.
  • Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes.