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Anti-Zebrafish gut secretory cell epitopes [FIS 2F11/2]


Catalogue Number 151483
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets Zebrafish gut secretory cell epitopes
Reactivity Zebrafish
Relevance The transparency of the juvenile zebrafish andits genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158). The antibody also labels hepatopancreatic ducts and intrahepatic bile ducts. enteroendocrine.
Host Mouse
Immunogen Lysate of zebrafish intestine
Subclass IgG1
Molecular Weight (kDa) 170, 120, 90 & 35
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested Dilution for western blot 1:500.

FIS 2F11/2 may also be used to stain stain formalin fixed tissue samples.
Research Area Aquaculture, Cell Cycle, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Developmental Biology, Epigenetics & Nuclear Signalling, Epitope Tags, Stem Cell Biology

References: 4 entries

Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.

Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.

Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.

Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.

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