Anti-TCP1 [84a (CTA-184)]
Invented at The Institute of Cancer Research
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151322 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | T-complex polypeptide 1 (TCP1) |
| Reactivity | Mouse |
| Relevance | TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. |
| Host | Rat |
| Immunogen | C-terminal half of the full length murine TCP protein |
| Positive Control | LK-35.2 cells |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 80 |
| Myeloma Used | Y3.AG.1.2.3 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | 84a can be used together with 91a for immunoprecipitation of CCT. |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cell Cycle |
References: 6 entries
Sternlicht et al. 1993. Proc Natl Acad Sci U S A. 90(20):9422-6. PMID: 8105476.
The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.
Europe PMC ID: 8105476
Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.
A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.
Europe PMC ID: 8335000
Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.
The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.
Europe PMC ID: 2655925
Add a reference
References: 6 entries
Sternlicht et al. 1993. Proc Natl Acad Sci U S A. 90(20):9422-6. PMID: 8105476.
The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.
Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.
A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.
Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.
The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.
Add a reference
