#151322

Anti-TCP1 [84a (CTA-184)]

Cat. #151322

Anti-TCP1 [84a (CTA-184)]

Cat. #: 151322

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: T-complex polypeptide 1 (TCP1)

Class: Monoclonal

Application: IP ; WB

Reactivity: Mouse

Host: Rat

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: The Institute of Cancer Research

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-TCP1 [84a (CTA-184)]
  • Clone: 84a (CTA-184)
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 80 kDa
  • Reactivity: Mouse
  • Host: Rat
  • Application: IP ; WB
  • Description: TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin.
  • Immunogen: C-terminal half of the full length murine TCP protein
  • Isotype: IgG2a
  • Myeloma used: Y3.AG.1.2.3
  • Recommended controls: LK-35.2 cells

Target Details

  • Target: T-complex polypeptide 1 (TCP1)
  • Molecular weight: 80 kDa
  • Tissue cell line specificity: LK-35.2 cells
  • Target background: TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin.

Applications

  • Application: IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Sternlicht et al. 1993. Proc Natl Acad Sci U S A. 90(20):9422-6. PMID: 8105476.
  • The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.
  • Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.
  • A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.
  • Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.
  • The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.