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Anti-BLM [BFL 103]

Invented by Helen Turley at University of Oxford

Info

Catalogue Number 151267
Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets Bloom’s Syndrome Protein (BLM)
Reactivity Human
Relevance BLM is the product of the Blooms syndrome gene and belongs to the RecQ family of DNA helicases. BLM is associated with an increase in the incidence of many types of cancer at an early age.
Host Mouse
Immunogen Recombinant Full Length Bloom’s Protein
Subclass IgG1
Positive Control Tonsil/thymus
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI + 10% FCS + HAT
Strain Balb/c
Research Area Cancer

References: 6 entries

Zhu et al. 2008. J Biol Chem. 283(43):29405-15. PMID: 18708356.

Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification.

Europe PMC ID: 18708356

Turley et al. 2001. Br J Cancer. 85(2):261-5. PMID: 11461087.

The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells.

Europe PMC ID: 11461087

Wu et al. 2000. J Biol Chem. 275(13):9636-44. PMID: 10734115.

The Bloom's syndrome gene product interacts with topoisomerase III.

Europe PMC ID: 10734115


Add a reference

References: 6 entries

Zhu et al. 2008. J Biol Chem. 283(43):29405-15. PMID: 18708356.

Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification.

Europe PMC ID: 18708356

Turley et al. 2001. Br J Cancer. 85(2):261-5. PMID: 11461087.

The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells.

Europe PMC ID: 11461087

Wu et al. 2000. J Biol Chem. 275(13):9636-44. PMID: 10734115.

The Bloom's syndrome gene product interacts with topoisomerase III.

Europe PMC ID: 10734115


Add a reference

References: 6 entries

Zhu et al. 2008. J Biol Chem. 283(43):29405-15. PMID: 18708356.

Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification.

Turley et al. 2001. Br J Cancer. 85(2):261-5. PMID: 11461087.

The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells.

Wu et al. 2000. J Biol Chem. 275(13):9636-44. PMID: 10734115.

The Bloom's syndrome gene product interacts with topoisomerase III.


Add a reference


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