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Anti-HIF2A [Hif2a 237]


Catalogue Number 151262
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Hypoxia-inducible factor 2, alpha subunit (HIF2A)
Reactivity Human
Relevance Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF2A is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF1A has been observed in varying subsets of tumour cells from various solid tumours. HIF2A is also a potent activator of the tie2 gene, which is known to be selectively expressed in endothelial cells.
Host Mouse
Subclass IgG2b
Myeloma Used P3/NS1/1-Ag4.1
Strain Balb/c
Research Area Cancer, Cardiovascular, Epigenetics & Nuclear Signalling, Metabolism

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