#151262

Anti-HIF2A [Hif2a 237]

Cat. #151262

Anti-HIF2A [Hif2a 237]

Cat. #: 151262

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Hypoxia-inducible factor 2, alpha subunit (HIF2A)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Helen Turley

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-HIF2A [Hif2a 237]
  • Clone: Hif2a 237
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF2A is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF1A has been observed in varying subsets of tumour cells from various solid tumours. HIF2A is also a potent activator of the tie2 gene, which is known to be selectively expressed in endothelial cells.
  • Isotype: IgG2b
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Hypoxia-inducible factor 2, alpha subunit (HIF2A)
  • Target background: Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF2A is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF1A has been observed in varying subsets of tumour cells from various solid tumours. HIF2A is also a potent activator of the tie2 gene, which is known to be selectively expressed in endothelial cells.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C