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Anti-XRCC3 [XRCC3 10F1/6]


Catalogue Number 151256
Applications WB
Antigen/Gene or Protein Targets XRCC3
Reactivity Human
Relevance X-Ray Repair Cross Complementing 3 (XRCC3) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC3 is also a component of the homologous recombination pathway.
Host Mouse
Immunogen His-tagged human XRCC3
Subclass IgG1
Positive Control HeLa nuclear extracts.
Molecular Weight (kDa) 37.8
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Bacteriology, DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 3 entries

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Masson et al. 2001. Proc Natl Acad Sci U S A. 98(15):8440-6. PMID: 11459987.

Tebbs et al. 1995. Proc Natl Acad Sci U S A. 92(14):6354-8. PMID: 7603995.

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