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Catalogue Number 151252
Applications ELISA IHC IP WB
Antigen/Gene or Protein Targets Kidins220/ARMS
Reactivity Rat
Relevance Kidins220/ARMS (Kinase D-Interacting Substrate of 220 kDa, ARMS; Ankyrin Repeat-rich Membrane Spanning) is an integral membrane protein that is selectively expressed in brain and neuroendocrine cells and phosphorylated by PKD (protein Kinase D). Kidins220 has also been shown to function downstream of the Trk and Eph receptor tyrosine kinases.
Host Mouse
Immunogen Recombinant GST-Kidins220/ARMS (last 347 amino acids at the carboxy terminus) fusion protein.
Subclass IgG1
Molecular Weight (kDa) 220
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cardiovascular, Cell Signaling & Signal Transduction, Neurobiology

References

There are 6 reference entries for this reagent.

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References: 6 entries

Deswal et al. 2013. J Immunol. 190(5):1927-35. PMID: 23359496.

Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells.

Europe PMC ID: 23359496

Bracale et al. 2007. Mol Biol Cell. 18(1):142-52. PMID: 17079733.

Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation.

Europe PMC ID: 17079733

Iglesias et al. 2000. J Biol Chem. 275(51):40048-56. PMID: 10998417.

Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D.

Europe PMC ID: 10998417


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References: 6 entries

Deswal et al. 2013. J Immunol. 190(5):1927-35. PMID: 23359496.

Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells.

Bracale et al. 2007. Mol Biol Cell. 18(1):142-52. PMID: 17079733.

Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation.

Iglesias et al. 2000. J Biol Chem. 275(51):40048-56. PMID: 10998417.

Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D.


Add a reference