Anti-Keratin15 [LHK15]
Invented at Queen Mary University of London
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151242 |
| Applications | ELISA FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | Keratin 15 |
| Reactivity | Bovine, Human, Mouse and Rat |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. |
| Host | Mouse |
| Immunogen | Peptide sequence of keratin 15 - BSA conjugate |
| Positive Control | Mouse colon tissue (IHC), A431 cells (IF), HepG2 cells (IF), COS7 cells (IF) |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5-10% FCS |
| Research Area | Cell Signaling & Signal Transduction |
References: 6 entries
Inoue et al. 2009. Lab Invest. 89(8):844-56. PMID: 19506554.
Differential expression of stem-cell-associated markers in human hair follicle epithelial cells.
Europe PMC ID: 19506554
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.
K15 expression implies lateral differentiation within stratified epithelial basal cells.
Europe PMC ID: 11092530
Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.
Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes.
Europe PMC ID: 10084315
Add a reference
References: 6 entries
Inoue et al. 2009. Lab Invest. 89(8):844-56. PMID: 19506554.
Differential expression of stem-cell-associated markers in human hair follicle epithelial cells.
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.
K15 expression implies lateral differentiation within stratified epithelial basal cells.
Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.
Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes.
Add a reference
