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Anti-Keratin15 [LHK15]


Catalogue Number 151242
Antigen/Gene or Protein Targets Keratin 15
Reactivity Bovine, Human, Mouse and Rat
Relevance Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes.
Host Mouse
Immunogen Peptide sequence of keratin 15 - BSA conjugate
Subclass IgG2a
Positive Control Mouse colon tissue (IHC), A431 cells (IF), HepG2 cells (IF), COS7 cells (IF)
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5-10% FCS
Research Area Cell Signaling & Signal Transduction

References: 3 entries

Inoue et al. 2009. Lab Invest. 89(8):844-56. PMID: 19506554.

Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.

Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.

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