Cat. #151242
Anti-Keratin15 [LHK15]
Cat. #: 151242
Unit size: 100 ug
Availability: 1-2 weeks
Target: Keratin 15
Class: Monoclonal
Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
Reactivity: Bovine ; Human ; Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Nick Tidman
Institute: Queen Mary University of London
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Keratin15 [LHK15]
- Clone: LHK 15
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Bovine ; Human ; Mouse ; Rat
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
- Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes.
- Immunogen: Peptide sequence of keratin 15 - BSA conjugate
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Mouse colon tissue (IHC), A431 cells (IF), HepG2 cells (IF), COS7 cells (IF)
Target Details
- Target: Keratin 15
- Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes.
Applications
- Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: DMEM + 5-10% FCS
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Waseem A et al. 1999. J. Invest. Dermatol. 112:362-9. PMID: 10084315 Porter RM et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530 Inoue K et al. Lab Invest. 2009 Aug
- 89(8):844-56. PMID: 19506554
