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Anti-Cdc27 [AF 3.1]


Catalogue Number 151232
Antigen/Gene or Protein Targets Cell division cycle protein 27 (cdc27)
Synonyms Cell Division Cycle 27; Anaphase Promoting Complex Subunit; D0S1430E; D17S978E; CDC27Hs; ANAPC3; H-NUC; APC3; Anaphase-Promoting Complex; Cell Division Cycle 27 Homolog; CDC27 Homolog; Nuc2 Homolog; HNUC; NUC2
Reactivity Mammalian and Xenopus laevis
Relevance Cdc27 is a component of the anaphase promoting complex (APC) which is responsible for destroying proteins, including cyclins, which are involved in mitosis. AF 3.1 is recommended for the immunoprecipitation of active APC.
Host Mouse
Immunogen A peptide corresponding to the C-terminal 10 residues of human cdc27 coupled to KLH.
Subclass IgG2b
Positive Control HeLa cells
Molecular Weight (kDa) 80
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cell Cycle, Protein Degradation

References: 5 entries

Mateo F et al. Oncogene. 2009 Jul 23;28(29):2654-66.

Ahlskog et al. 2010. Mol Cell Biol. 30(24):5608-20. PMID: 20937767.

Holt et al. 2010. Development. 137(8):1297-304. PMID: 20223764.

Hochegger et al. 2007. J Cell Biol. 178(2):257-68. PMID: 17635936.

Yamano et al. 1998. EMBO J. 17(19):5670-8. PMID: 9755167.

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