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Anti-CD14 [UCH-M1]

Invented by Prof Peter Beverley at Imperial College

Info

Catalogue Number 151174
Applications FACS IHC IF
Antigen/Gene or Protein Targets CD14
Synonyms CD14 Molecule; CD14 Antigen; Myeloid Cell-Specific Leucine-Rich Glycoprotein
Reactivity Human
Relevance CD14 is found in human monocytes and vascular endothelium in some tissues. CD14 binds the endotoxin lipopolysaccharide. UCH-M1 can be used to investigate specific in vitro antibody responses to influenza virus by human lymphocytes.
Host Mouse
Immunogen Thymocytes and peripheral blood leucocytes (PBL)
Subclass IgG2a
Molecular Weight (kDa) 52
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes UCH-M1 activates complement
Research Area Cardiovascular, Cell Type or Organelle Marker, Immunology, Stem Cell Biology

References: 10 entries

Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.

GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.

Europe PMC ID: 27695085

Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.

Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.

Europe PMC ID: 16927388

Puig-Kröger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901.

Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.

Europe PMC ID: 15070901

Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.

Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.

Europe PMC ID: 6389324

Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.

Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.

Europe PMC ID: 6578194


Add a reference

References: 10 entries

Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.

GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.

Europe PMC ID: 27695085

Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.

Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.

Europe PMC ID: 16927388

Puig-Kröger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901.

Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.

Europe PMC ID: 15070901

Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.

Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.

Europe PMC ID: 6389324

Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.

Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.

Europe PMC ID: 6578194


Add a reference

References: 10 entries

Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.

GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.

Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.

Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.

Puig-Kröger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901.

Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.

Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.

Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.

Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.

Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.


Add a reference


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