Anti-CD14 [UCH-M1]
Invented by Prof Peter Beverley from Imperial College
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 151174 |
| Applications | FACS IHC IF |
| Antigen/Gene or Protein Targets | CD14 |
| Synonyms | CD14 Molecule; CD14 Antigen; Myeloid Cell-Specific Leucine-Rich Glycoprotein |
| Reactivity | Human |
| Relevance | CD14 is found in human monocytes and vascular endothelium in some tissues. CD14 binds the endotoxin lipopolysaccharide. UCH-M1 can be used to investigate specific in vitro antibody responses to influenza virus by human lymphocytes. |
| Host | Mouse |
| Immunogen | Thymocytes and peripheral blood leucocytes (PBL) |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 52 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | UCH-M1 activates complement |
| Research Area | Cardiovascular, Cell Type or Organelle Marker, Immunology, Stem Cell Biology |
References: 10 entries
Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.
GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.
Europe PMC ID: 27695085
Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.
Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.
Europe PMC ID: 16927388
Puig-Kröger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901.
Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.
Europe PMC ID: 15070901
Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
Europe PMC ID: 6389324
Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.
Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.
Europe PMC ID: 6578194
Add a reference
References: 10 entries
Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.
GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.
Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.
Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.
Puig-Kröger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901.
Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.
Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.
Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.
Add a reference
