Cat. #151174
Anti-CD14 [UCH-M1] mAb
Cat. #: 151174
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD14
Class: Monoclonal
Application: FACS ; IHC ; IF
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Peter Beverley
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-CD14 [UCH-M1] mAb
- Alternate name: CD14 Molecule; CD14 Antigen; Myeloid Cell-Specific Leucine-Rich Glycoprotein
- Clone: UCH-M1
- Tool type ecom: Antibodies
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 52 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF
- Description: UCH-M1 can be used to investigate specific in vitro antibody responses to influenza virus by human lymphocytes.
- Immunogen: Thymocytes and peripheral blood leucocytes (PBL)
- Immunogen uniprot id: P08575
- Isotype: IgG2a
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: CD14
- Molecular weight: 52 kDa
- Target background: CD14 is found in human monocytes and vascular endothelium in some tissues. CD14 binds the endotoxin lipopolysaccharide.
Applications
- Application: FACS ; IHC ; IF
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-CD45RO, Recombinant [UCH-L1]
References
- Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.
- GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.
- Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.
- Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.
- Puig-Kr
ger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901. - Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.
- Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
- Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
- Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.
- Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.
