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Anti-CD44 [P2A1]

Invented at Queen Mary University of London

Info

Catalogue Number 151139
Applications FACS IHC IF IP
Antigen/Gene or Protein Targets CD44
Synonyms CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP90 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
Reactivity Human
Relevance CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.
Host Mouse
Immunogen Ocular melanoma cell line (V+B2)
Subclass IgG2a
Molecular Weight (kDa) 95
Recommended Growing Conditions DMEM + 5% FCS
Research Area Adhesion, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology

References

There are 6 reference entries for this reagent.

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References: 6 entries

The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.

Europe PMC ID: 27079967

Glatt et al. 2016. Mol Pharm. :. PMID: 27079967.

FACS

Bains et al. 2002. Fertil Steril. 78(2):307-12. PMID: 12137867.

Human sperm cells express CD44.

Europe PMC ID: 12137867

Nath et al. 1999. Immunology. 98(2):213-9. PMID: 10610356.

Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin.

Europe PMC ID: 10610356


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References: 6 entries

The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.

Glatt et al. 2016. Mol Pharm. :. PMID: 27079967.

FACS

Bains et al. 2002. Fertil Steril. 78(2):307-12. PMID: 12137867.

Human sperm cells express CD44.

Nath et al. 1999. Immunology. 98(2):213-9. PMID: 10610356.

Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin.


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Inventor Information

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