#151139

Anti-CD44 [P2A1]

Cat. #151139

Anti-CD44 [P2A1]

Cat. #: 151139

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: CD44

Class: Monoclonal

Application: FACS ; IHC ; IF ; IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: John Marshall

Institute: Queen Mary University of London

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-CD44 [P2A1]
  • Alternate name: CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP9 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
  • Clone: P2A1
  • Tool type ecom: Antibodies
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 95 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; IP
  • Description: CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.
  • Immunogen: Ocular melanoma cell line (V+B2)
  • Isotype: IgG2a
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: CD44
  • Molecular weight: 95 kDa
  • Target background: CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.

Applications

  • Application: FACS ; IHC ; IF ; IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.
  • Glatt et al. 2016. Mol Pharm. :. PMID: 27079967.
  • Bains et al. 2002. Fertil Steril. 78(2):307-12. PMID: 12137867.
  • Human sperm cells express CD44.
  • Nath et al. 1999. Immunology. 98(2):213-9. PMID: 10610356.
  • Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin.