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Anti-NCAM [ERIC-1]

Invented by Dr JOHN KEMSHEAD at SHIRE PHARMACEUTICALS

Info

Catalogue Number 151092
Applications ELISA FACS IHC IF IP RIA WB
Antigen/Gene or Protein Targets Neural Cell Adhesion Molecule (NCAM; CD56)
Synonyms Neural Cell Adhesion Molecule; NCAM; CD56 Antigen; MSK39
Reactivity Human
Relevance NCAM, also known as CD56, is a homophillic binding glycoprotein present on a variety of neural cells including neurons, glia, skeletal muscle and natural killer cells. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synatptic plasticity, learning and memory and in the development of the nervous system.
Host Mouse
Immunogen Retinoblastoma tissue membrane fraction
Subclass IgG1
Positive Control Neuroblastome
Molecular Weight (kDa) 180, 140, 120
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes In the mouse brain, 3 main isoforms have been described of 180,140 and 120 kDa MW. A Western blot of 2 year old pediatric brain revealed bands of 180,140 and 120 kDa (weakly) with ERIC-1.
Research Area Adhesion, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Neurobiology, Stem Cell Biology

References: 9 entries

Marković-Lipkovski et al. 2015. PLoS One. 10(9):e0137028. PMID: 26327314.

IHC IF

Klehr et al. 2009. J Immunother. 32(5):442-51. PMID: 19609236.

FACS IP

Pruszak et al. 2007. Stem Cells. 25(9):2257-68. PMID: 17588935.

Blaheta et al. 2004. Neoplasia. 6(4):323-31. PMID: 15256054.

FACS

Jensen et al. 2003. Clin Exp Immunol. 134(2):253-63. PMID: 14616785.

FACS

Gerardy-Schahn et al. 1994. Int J Cancer Suppl. 8:38-42. PMID: 7515028.

WB

Phimister et al. 1991. J Clin Pathol. 44(7):580-5. PMID: 1856291.

Frost et al. 1991. Neuropathol Appl Neurobiol. 17(3):207-17. PMID: 1891065.

Bourne et al. 1991. J Neurooncol. 10(2):111-9. PMID: 1895159.


Add a reference

References: 9 entries

Marković-Lipkovski et al. 2015. PLoS One. 10(9):e0137028. PMID: 26327314.

IHC IF

Klehr et al. 2009. J Immunother. 32(5):442-51. PMID: 19609236.

FACS IP

Pruszak et al. 2007. Stem Cells. 25(9):2257-68. PMID: 17588935.

Blaheta et al. 2004. Neoplasia. 6(4):323-31. PMID: 15256054.

FACS

Jensen et al. 2003. Clin Exp Immunol. 134(2):253-63. PMID: 14616785.

FACS

Gerardy-Schahn et al. 1994. Int J Cancer Suppl. 8:38-42. PMID: 7515028.

WB

Phimister et al. 1991. J Clin Pathol. 44(7):580-5. PMID: 1856291.

Frost et al. 1991. Neuropathol Appl Neurobiol. 17(3):207-17. PMID: 1891065.

Bourne et al. 1991. J Neurooncol. 10(2):111-9. PMID: 1895159.


Add a reference

References: 9 entries

Marković-Lipkovski et al. 2015. PLoS One. 10(9):e0137028. PMID: 26327314.

IHC IF

Klehr et al. 2009. J Immunother. 32(5):442-51. PMID: 19609236.

FACS IP

Pruszak et al. 2007. Stem Cells. 25(9):2257-68. PMID: 17588935.

Blaheta et al. 2004. Neoplasia. 6(4):323-31. PMID: 15256054.

FACS

Jensen et al. 2003. Clin Exp Immunol. 134(2):253-63. PMID: 14616785.

FACS

Gerardy-Schahn et al. 1994. Int J Cancer Suppl. 8:38-42. PMID: 7515028.

WB

Phimister et al. 1991. J Clin Pathol. 44(7):580-5. PMID: 1856291.

Frost et al. 1991. Neuropathol Appl Neurobiol. 17(3):207-17. PMID: 1891065.

Bourne et al. 1991. J Neurooncol. 10(2):111-9. PMID: 1895159.


Add a reference


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