Anti-CyclinA [E43.2]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151089 |
| Applications | WB |
| Antigen/Gene or Protein Targets | Cyclin A |
| Synonyms | CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146 |
| Reactivity | Human |
| Relevance | Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase. E43.2 is excellent for detecting cyclin A, giving a strong signal with no background. |
| Host | Mouse |
| Immunogen | Human Cyclin A |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | Recommended Concentration: 1ug/ml |
| Research Area | Cancer, Cell Cycle, Epigenetics & Nuclear Signalling |
References: 2 entries
Ahmed-Choudhury et al. 2005. Cancer Res. 65(7):2690-7. PMID: 15805267.
Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter.
Europe PMC ID: 15805267
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References: 2 entries
Ahmed-Choudhury et al. 2005. Cancer Res. 65(7):2690-7. PMID: 15805267.
Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter.
Add a reference
