Cat. #151089
Anti-CyclinA [E43.2]
Cat. #: 151089
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Cyclin A
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-CyclinA [E43.2]
- Alternate name: CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146
- Clone: E43.2
- Tool type ecom: Antibodies
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: E43.2 is excellent for detecting cyclin A, giving a strong signal with no background.
- Immunogen: Human Cyclin A
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Cyclin A
- Target background: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Ahmed-Choudhury et al. 2005. Cancer Res. 65(7):2690-7. PMID: 15805267.
- Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter.
