Anti-IL12 [1-1D5]
Invented at University of Leeds
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151023 |
| Applications | ELISA IHC Fn RIA WB |
| Antigen/Gene or Protein Targets | Interleukin-12 (IL12) p40 subunit |
| Synonyms | Interleukin 12; Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit; NK Cell Stimulatory Factor Chain; Interleukin-12 Beta Chain; IL-12 Subunit P40; CLMF P40; NKSF2; Natural Killer Cell Stimulatory Factor; IL12; Subunit P40; Interleukin 12; CLMF2; IMD29; NKSF; P40 |
| Reactivity | Human |
| Relevance | IL-12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL-12 plays a central role in cell-mediated immunity, promoting the differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL-12 is a potent stimulator of Natural Killer cells. IL-12 therapy has been suggested as a method of enhancing cytocidal anti-tumour immune responses. |
| Host | Mouse |
| Immunogen | Recombinant human IL-12 produced by baculovirus. |
| Subclass | Not Known |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS. |
| Research Area | Immunology |
References: 2 entries
Carter et al. 1997. Hybridoma. 16(4):363-9. PMID: 9309427.
Production and characterization of monoclonal antibodies to human interleukin-12.
Europe PMC ID: 9309427
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References: 2 entries
Carter et al. 1997. Hybridoma. 16(4):363-9. PMID: 9309427.
Production and characterization of monoclonal antibodies to human interleukin-12.
Add a reference
