TcAg1 small molecule (tool compound)
Invented by David Smith , Zelong Lim , Elizabeth New
Invented at University of Sydney
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 160762 |
| Antigen/Gene or Protein Targets | Ag (I) ions |
| Synonyms | Thiocoumarin silver sensor 1 |
| Type | Fluorescent Probe |
| Relevance |
Silver is widely used in industrial applications due to its conductivity and malleability properties, as well as in medicine as an antibiotic coating and in wound treatment. The high toxicity of silver is crucial for the unique antibacterial properties of this metal, but there is concern about the effect of aquatic silver pollution on the fresh water invertebrates and fish. Traditional instrument methods for measuring silver include CIP-MS, GFAAS and voltammetry. However, these techniques require sample preparation or digestion and complex instruments and trained operators, and they lack the ability to differentiate between metallic silver, precipitated silver salts and complexes and free Ag(I). Here an alternative approach has been developed using a fluorescent sensor that can selectively and reversibly respond to Ag(I) ions in solution. |
| Selectivity | Ag(I) ions only |
| Molecular Formula | C20N2S2OH18 |
| Key Attributes | Fluorescence excitation at 470nm and emission peak at 565nm |
| lUPAC | 3-(3-Benzoxazolyl)-7-(diethylamino)-2H-1-benzopyran-2-one |
| In vitro applications | Reversible fluorescent probe for monitoring Ag (I) ions |
| Research Area | Other |
| Notes | For application notes please visit PMID:30021927 |
References: 1 entry
References: 1 entry
Inventor Information
Inventors
|
David Smith |
|
|
Zelong Lim |
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Elizabeth New |
