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Anti-DJ-1 [E2-1A] monoclonal antibody
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Info

Catalogue Number 160671
Applications IHC WB
Antigen/Gene or Protein Targets DJ-1
Synonyms PARK7
Reactivity Human
Relevance DJ-1 is a broadly conserved protein among both prokaryotic and eukaryotic cells. It has been identified as playing a diverse role in a range of cellular processes. DJ-1 was originally proposed to be a pro-oncogene, and has since been shown to be expressed at varying levels in breast, non-small cell lung and prostate cancer. It has been demonstrated to paly a role in the regulation of RNA-binding proteins as well as the regulation of testicular androgen receptors and fertilization. In addition, mutations in DJ-1 have been linked to autosomal recessive early-onset familial Parkinson's disease, and have been shown to be a key component of the oxidative stress and ubiquitin-proteasome system response (see Hod, 2004 PMID: 15258905 for additional details).
Host Mouse
Immunogen Full length recombinant human DJ-1
Subclass IgM
Molecular Weight (kDa) 24
Notes Hybridoma cell line
Research Area Cancer, Reproductive Biology, Neurobiology, Apoptosis and Programmed Cell Death

References

There are 2 reference entries for this reagent.

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References: 2 entries

Hod et al. 2004. J Cell Biochem. 92(6):1221-33. PMID: 15258905.

Hod et al. 1999. J Cell Biochem. 72(3):435-44. PMID: 10022524.


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References: 2 entries

Hod et al. 2004. J Cell Biochem. 92(6):1221-33. PMID: 15258905.

Hod et al. 1999. J Cell Biochem. 72(3):435-44. PMID: 10022524.


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