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Monoclonal Antibodies

Anti-LPS Hafnia alvei PCM 1186 [HA1186] monoclonal antibody

Invented by Tomasz Lipiński
Invented at Polish Center for Technology Development/Polski Ośrodek Rozwoju Technologii (PORT)
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Catalogue Number 160655
Applications ELISA WB DB
Antigen/Gene or Protein Targets O antigen part of the lipopolysaccharide from Hafnia alvei PCM 1186
Reactivity N/A
Relevance Lipopolysaccharde is the major constituent of the outer membrane of Gram-negative bacteria. It is composed of lipid A covalently joined with polysaccharide in which 3 regions are structurally defined: inner core, outer core and O-antigen. LPS is a potent activator of immune response and is responsible for toxic effects when introduced to an organism. O-antigens is a polymer of different length and composition built of repetitive oligosaccharide units. O-antigen is the most variable region of LPS and defines strain specificity of bacteria, therefore is used as an antigen in serotyping with specific sera or monoclonal antibody.
Immunogen Whole Hafnia alvei PCM 1216 bacteria
Molecular Weight (kDa) approx 150kDa
Notes The product may be useful for the Hafnia alvei strain serotyping, detection of LPS in WesterBlot, Dot Blot or similar techniques
Research Area Bacteriology, Microbiology

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