Anti-Ly-49A [YE1/32.8.5] monoclonal antibody
Invented at BC Cancer
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 160511 |
| Applications | FACS IP |
| Antigen/Gene or Protein Targets | Ly-49A |
| Reactivity | Mouse |
| Relevance | The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk. |
| Host | Rat |
| Immunogen | ECA17.9.8 cells |
| Subclass | IgG2b |
| Molecular Weight (kDa) | 44 |
| Myeloma Used | Y3 |
| Notes |
This antibody is suitable for functional studies in addition to flow and IP studies. This antibody is not suitable for western blotting. This antibodies does not cross react with other Ly-49A molecules. |
| Research Area | Immunology, Cancer |
References: 2 entries
Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883.
Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191.
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References: 2 entries
Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883.
Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191.
Add a reference
