Anti-FN-EDB polyclonal antibody
Invented at University of Tartu
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 160465 |
| Applications | ELISA IHC |
| Antigen/Gene or Protein Targets | extra domain B of fibronectin, EDB-FN |
| Reactivity | Human |
| Relevance |
Oncofetal fibronectin (FN-EDB) and tenascin-C C domain (TNC-C) are nearly absent in extracellular matrix of normal adult tissues but upregulated in malignant tissues. Both FN-EDB and TNC-C are developed as targets of antibody-based therapies. This series of antibodies has been validated in vitro against glioblastoma (GBM) and prostate carcinoma xenografts, and to non-malignant angiogenic neovessels induced by VEGF-overexpression. Please see our related anti-FN-EDB antibodies from University of Tartu. |
| Host | Rabbit |
| Research Area | Cancer |
